Introduction to Adaptive Trial Designs using FACTS: Phase 2 Arm Dropping and RAR
In this video we look at designing response adaptive randomization (RAR) and arm dropping multi-arm phase 2 trials.
Introduction to Adaptive Trial Designs using FACTS: Group Sequential Designs
In this video we look at designing Group Sequential trials for confirmatory phase 3 trials, where the trial includes interims to stop early for efficacy and futility.
Introduction to Adaptive Trial Designs using FACTS: Phase 1 Dose Escalation
In this video we look at the issues around designing Phase 1 Dose Escalation trials in oncology, where the aim is to explore increasing dose levels up to a limiting rate of toxicities.
The Implementation of Platform Trials for ALS Research
Dr. Melanie Quintana, statistical scientist and director at Berry Consultants, discussed innovative clinical trial design in ALS research at the 2023 MDA conference.
Adaptive Platform Clinical Trials: Application to ILD
Roger J. Lewis, MD, PhD, lectured on REMAP-ILD at HCOR scientific meeting (Sao Paulo, Brazil).
JAMAevidence Podcast Series: Time-to-Event Analysis with Dr. Juliana Tolles
This Podcast series by JAMA provides valuable interviews about the statistical and methodological foundations of clinical research.