Publications
Where expertise meets impact
Berry doesn’t just follow industry standards — we set them. Our team of award-winning statisticians, journal editors, and regulatory advisors leads the field in Bayesian and adaptive clinical trial design. With research published in The New England Journal of Medicine, JAMA, and The Lancet, we’re driving innovation where it matters most.
Over 90% of our scientists published influential work this past year, advancing adaptive, Bayesian, and platform trial methodology. Our blend of academic rigor, regulatory insight, and real-world experience makes Berry a true authority in modern clinical trials.
Explore our most impactful peer-reviewed publications below.

Pharmaceutical Statistics
Psychiatry
Micturiation
Design Considerations for a Phase II Platform Trial in Major Depressive Disorder
August 27, 2025
2025
doi: 10.1002/pst.70025
Bulletin of the World Health Organization
Methodology
Ethical clinical trial design and differences in treatment effects
August 25, 2025
2025
doi: 10.2471/BLT.24.292177

Journal of Clinical Medicine
Methodology
Bayesian Drug Development
Adaptive Bayesian Clinical Trials: The Past, Present, and Future of Clinical Research
July 25, 2025
2025
DOI: 10.3390/jcm14155267
BMJ Journals
Infectious Disease
Platform
Tocilizumab, sarilumab and anakinra in critically ill patients with COVID-19: a randomised, controlled, open-label, adaptive platform trial
July 15, 2025
2025
DOI: 10.1136/thorax-2024-222488
American Journal of Respiratory and Critical Care Medicine
Extracorporeal Membrane Oxygenation (ECMO)
Methodology
Development of a New Longitudinal Ordinal Outcome for Clinical Trials in Extracorporeal Membrane Oxygenation Patients
July 1, 2025
2025
doi: 10.1164/rccm.202408-1582OC

Science Direct
Sepsis
Stopping Rules
Design and methods of an adaptive trial to test comparative effectiveness of readmission reduction approaches following infection and sepsis hospitalizations (ACCOMPLISH)
June 19, 2025
2025
DOI: 10.1016/j.conctc.2025.101504
ATS
Mechanical Ventilation
Historical Borrowing
Temporary Transvenous Diaphragm Neurostimulation for Weaning from Mechanical Ventilation (RESCUE-3)
June 11, 2025
2025
DOI: 10.1164/rccm.202505-1056OC
Statistics in Medicine
Methodology
Stopping Rules
Predictive Probabilities Made Simple: A Fast and Accurate Method for Clinical Trial Decision-Making
June 1, 2025
2025
DOI: 10.1002/sim.70120
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