Therapeutic Areas / Diseases
We have experience working on clinical trials across the FDA’s therapeutic areas, including many different syndromes, diseases, and other chronic and communicable conditions. Below is a summary of just some of the areas we have constructed adaptive designs in, with many others in progress.
| Aging | Extracorporeal Membrane Oxygenation (ECMO) | Osteosarcoma |
| Alexander Disease | Frontotemporal Disorders | Other Orphan Diseases |
| Alopecia | Essential Tremors | Pain |
| Amyotrophic Lateral Sclerosis | Gastroparesis | Parkinsons |
| Angelman Syndrome | Glioblastoma | Pancreatic Cancer |
| Angioplasty | Heart Failure | Patent Foramen Ovale |
| Antimicrobial Resistance | Hemophilia | Pelizaeus-Merzbacher Disease (PMD) |
| Asthma | Hemorrhage | PO Ileus |
| Atrial Fibrillation | Hepatitis C | Post Traumatic Stress Disorder (PTSD) |
| Bladder Cancer | Hepatorenal Syndrome | Preterm Labor |
| Breast Cancer | HIV | Prion Disease |
| Calciphylaxis | Hydrocephalus | Pulmonary Arterial Hypertension |
| Cancer Diagnostics | Idiopathic Pulmonary Fibrosis (IPF) | Retinitis Pigmentosa |
| Cardiac Arrest | Immunoglobulin A Nephropathy (IgAN) | Rett Syndrome |
| Chronic Kidney Disease | Interstitial Lung Disease | Rheumatoid Arthritis |
| Chronic Lymphocytic Leukemia | Kennedy's Disease | Schizophrenia |
| Clostridioides Difficile (C. Diff) | Lupus | Sepsis |
| Community Acquired Pneumonia | Lyme's Disease | Sepsis-Associated Acute Kidney Injury |
| Congestive Heart Failure | Micturiation | Sexual Health |
| Constipation | Migraine | Shingles |
| Contraceptives | Mitral Valve Regurgitation | Sleep Apnea |
| COVID-19 | Monkeypox/MPox | Smoking Cessation |
| Crohns | MPS IIIA Disease | Spinal Cord Injury |
| Cushing's Disease | Multiple Myeloma | Staphylococcus Aureus |
| Cytomegalovirus | Multiple Sclerosis | Statins |
| Deep Vein Thrombosis | Myotonic Dystrophy | Stroke |
| Diabetes | Nasal Congestion | STXBP1 Encephalopathy |
| Diffuse Large B-Cell Lymphoma | Nasal Polyps | Thrombectomy |
| Disc Disease | Necrotizing Enterocolitis | Tinnitus |
| Drooling | Netherton Disease | Transcatheter Aortic Valve Replacement |
| Duchenne Muscular Dystrophy | Neuroendocrine Tumors | Traumatic Brain Injury (TBI) |
| Elective Surgery | Non Small Cell Lung Cancer | Treatment Resistant Depression (TRD) |
| Emesis | Nonalcoholic Steatohepatitis | Tricuspid Valve Regurgitation |
| Emphysema | Obesity | Ulcerative Colitis |
| ENPP-1 Deficiency | Oncology | Valves / Stents |
| Epilepsy with Myoclonic-Atonic Seizures | Osteoparesis | Vasospasm |
| X-Linked Dystonia Parkinsonism |