Webinars and Videos

In this episode of "In the Interim…", Dr. Scott Berry examines three recent health-research headlines through a statistician's lens: an Adventist Health Study-2 analysis, an Emory University trial, and a British Medical Journal study.

In this episode of "In the Interim...", Dr. Scott Berry dissects prevailing concepts of “clinically meaningful difference” in clinical trials focusing on progressive diseases.

Designing a group sequential phase 3 with a long time to final endpoint, using longitudinal modelling and Bayesian predictive probabilities for decision making at the interims.

Designing a trial with three arms compared to placebo and Active Comparator, using two endpoints: an early endpoint to compare to PBO for futility & arm selection in phase 2, and a late efficacy endpoint to compare against the AC.

Designing a platform trial to test several assets in the same indication that will become available over time.

Designing a phase 2 trial to determine for which of four rare tumours a treatment is effective. Looking at separate analyses, pooled analysis and using a hierarchical model to borrow across groups.