Get better Answers
With Innovative, Adaptive Clinical Trials.

Berry Consultants ("Berry") is a scientific consulting company specializing in innovative adaptive clinical trial design, analysis, implementation, and software solutions for the pharmaceutical and medical device industry.

Biological structures and spirals.
What We Do

To seek efficient answers for new medical advancements, you need more. That’s why Berry offers innovative statisticians and software for the freedom to design and implement adaptive clinical trials. Get the answers you need from analysis to approval and beyond.

How We Do It

Innovative Trials, Better Outcomes.

Berry has extensive experience in the design, implementation, and software solutions of adaptive clinical trials across many medical disciplines. Adaptive trials can result in better insights, greater efficiency, better treatment for subject in a trial, and better information for regulators and the medical community. Here’s the Adaptive Trial Process.

A flow chart showing the process from data collection to stopping trial.
Services & Software

Adaptive Clinical Trial Design

Allow the pre-specification of flexible components to the major aspects of a trial, like the treatment arms, the allocation to the different treatment arms, the patient population, and the sample size.

Trial Implementation

Our services include interim and final analyses for primary and key secondary efficacy endpoints, providing expert guidance on best practices for adaptive design implementation, and interacting with Data Safety Monitoring Boards (DSMB) for adaptive and platform trials.

Clinical Trial Software

Software solutions that help Biostatisticians rapidly design, compare, and simulate both fixed and adaptive trial designs through powerful, versatile and fast simulation tools.

Platform Trials

Innovative clinical trials that evaluate multiple treatments simultaneously and intended to continue beyond the evaluation of any one treatment, while maximizing statistical and clinical efficiency.

Latest News and Events

Biological structures and spirals.
Event

New Publication: Dr. Donald Berry on the Evolution of Bayesian Clinical Trials

Dr. Donald Berry has published a comprehensive history from his perspective on the development of Bayesian clinical trials, entitled “Adaptive Bayesian Clinical Trials: The Past, Present, and Future of Clinical Research.” It’s available free with open access from the publisher at https://www.mdpi.com/2077-0383/14/15/5267

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August 20, 2025
New Publication: Dr. Donald Berry on the Evolution of Bayesian Clinical Trials
August 20, 2025
Biological structures and spirals.
Event

Episode 25, “A Discussion with Michael Proschan on Response-Adaptive Randomization”

In this episode of "In the Interim…", Dr. Scott Berry and NIH’s Dr. Michael Proschan conduct a detailed discussion from opposing viewpoints on response-adaptive randomization (RAR) in clinical trials.

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August 18, 2025
Episode 25, “A Discussion with Michael Proschan on Response-Adaptive Randomization”
August 18, 2025
Biological structures and spirals.
Event

Episode 24, “STEP Statistical Modeling”

In this episode of "In the Interim…", Dr. Scott Berry, Dr. Elizabeth Lorenzi, and Dr. Amy Crawford discuss the STEP platform trial’s statistical methodology for evaluating which acute stroke patients benefit and which do not from endovascular therapy (EVT).

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August 11, 2025
Episode 24, “STEP Statistical Modeling”
August 11, 2025
Biological structures and spirals.
Event

Episode 23, “Bayesian Approach in Clinical Trials”

This episode of "In the Interim…" features Dr. Scott Berry, Dr. Kert Viele, and Dr. Melanie Quintana of Berry Consultants dissecting the technical and operational landscape of Bayesian statistics in clinical trial design.

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August 4, 2025
Episode 23, “Bayesian Approach in Clinical Trials”
August 4, 2025